WeAreBodyBeautiful's round-up of the best lash serums for luscious lashes

The best eyelash growth serums compared

Big fluttery lashes.

That are REAL. And if you’ve got around $50/£40 spare noodle, then in just a month or so time, you can have them too!

This is what fancy lash enhancing serums promise you.

And I do rather like the idea of no-effort luscious lashes day after day. So, if these serums make my natural lashes look like I’m already wearing mascara, I’ll defo give them a go.

The most popular lash enhancing serums - but which is best?
The most popular lash serums – but are they worth it?

But hang on a minute

What’s in these magic potions, how do they work, and are they even safe?

Well, hold onto your socks. Here we go again with another WeAreBodyBeautiful roundup review of the best lash enhancing & growth serums!

Here are the serums we’ll take a closer look at and compare:

UKLash SILLY GEORGE RapidLash GrandeLASH-MD LASHFOOD REVITALASH® Advanced neuLASH®
What is it?
Eyelash serum

Lash Growth serum

Eyelash enhancing serum

Lash Enhancing Serum

Lash enhancer

Eyelash conditioner & serum

Lash enhancing serum
Price
Amount
Lasts
£37.99
3 ml
3 months
£44.99
3ml
2-3 months
$49.95/ £39.99
3 ml
2 months
$65/£55
2ml
3 months
$78
3 ml
3 months
$98 / £125
2ml
3 months
$150
6ml
6months
What it does Fortifies your lash follicles to visibly boost length & improve volume. Activates the hair follicle for rapid growth.
Also toughens the epidermal junction to prevent fall out.
Conditions, hydrates, fortifies, and nurtures lashes. Naturally stimulates hair growth, protects, conditions & hydrates. Prevents hair loss & triggers regrowth of lashes. Protects against breakage, conditions, improves health, flexibility & strength, revitalise, add shine, fortify & smooth. Protects, conditions, enhance, elasticity, shine, strength.
Good to know ✔Cruelty free
✔Vegan friendly
✔Cruelty free
✔Vegan friendly
✔Cruelty free
✔Cruelty free
🐇PETA certified
🌿Ecocert certified
✔Cruelty free
🐇PETA certified
✔Vegan friendly
✔Cruelty free
🐇PETA certified
✔Vegan friendly
✔Cruelty free
Guarantee? ✔ 12-week limited guarantee (based on before/after photos) ✔ 60-day money back guarantee ✔180-day money back guarantee
Deals 🌍 🇬🇧 🇦🇺 🇺🇸 UKLash.com 🌍 🇬🇧 🇦🇺 🇺🇸 sillygeorge.com 🇬🇧 allbeauty.com
🇺🇸 LookFantastic US
🇬🇧 allbeauty.com
🇺🇸 Skinstore US
🇺🇸 LASHFOOD.com 🇬🇧 Amazon UK
🇺🇸 Amazon.com
🇺🇸 skinresearchlabs.com

In this eyelash growth serum review:

Where did eyelash serums come from?

Eyelash enhancing serums have been around for almost ten years now and there are loads of brands available today. They’re cosmetics, just like make-up and shampoo, so you can buy them over-the-counter (OTC) in shops and from online stores.

But they didn’t start out this way. It all began with a licensed and FDA-approved medication for eyes, called Lumigan.

Ophthalmologists prescribe Lumigan to treat patients with glaucoma. A few drops placed inside the eye helps control intraocular pressure. A side effect in most patients is they grow extremely long lashes in their treated eye.

Latisse prescription medicine for lash growth
Latisse lash growth serum is the same drug as Lumigan for glaucoma

Allergan, the manufacturer of Lumigan, saw this opportunity and in 2009 patented the same drug for use as prescription-strength eyelash growth serum. They called it LatisseTM.

The active lash-growing ingredient in Latisse is a prostaglandin analog called bimatoprost.

Prosta-what-now?

Prostagladin analogs & bimatoprost

Prostaglandins are a group of physiologically active substances with diverse hormonelike effects in animals. They’re found in nearly all the tissues in our bodies and the various structures/types of prostaglandin affect different biological activities. These prostaglandins are lipid compounds from fatty acids, and they bind to prostaglandin receptors.

The chemical structure diagram of the prostaglandin analog called Bimatoprost found in glaucoma medication and eye lash growth medicinal serum
The chemical structure of bimatoprost prostaglandin used to treat glaucoma

So, bimatoprost prostaglandin works because it activates Prostamide Alpha F2 receptors in the hair follicle (primarily the dermal papilla and outer root sheath) to stimulate growth. It’s not known how it works exactly, but it’s thought to influence the development and regrowth of the hair follicle. It causes an increase in the duration of and number of hairs in the active “Anagen” growing stage. So, your lashes grow longer and are fuller because there’s more of them sprouting. Yay!

Diagram showing the hair growth cycle with a large hair follicles in Anagen growth, a grown catagen hair detaching from the bulb, a telegon hair no longer growing and retracting out the follicle, and an early anagen hair growing in the hair follicle bulb area again.
Bimatoprost gives more lashes in a longer Anagen growth stage

Allergan patented the use of bimatoprost in Lumigan and Latisse, which means others can’t use it. So, those wily cosmetic brands made synthetic copies of bimatoprost which probably have the same growth effect on the lashes.

Lash serums containing prostaglandin analogs:

GrandeLash-MD   

RapidLash

neuLash

These synthetic prostaglandins in the ingredients list of these lash serums are:

  • Choprestenol isopropyl
  • Isopropyl cloprestonate
  • and Cloprostenol isopropylester

But such serums are still cosmetics, which means they’re much less potent than the medication Latisse. Let’s learn how next…

Lash enhancing vs Lash growth?

First, you’ll notice these synthetic prostaglandin analog ingredients very far down, or even at the end, of the ingredients list. This means there’s not very much of it in the serum.

Why is this?

A serum with a high concentration of synthetic prostaglandin analog is exactly like the drug Latisse; it causes changes in your hair follicles to grow hair. Such serums would require licensing and approval by each coutries governing bodies, and a prescription from a doctor too. So, keeping the concentration very low reduces the effect, and keeps it within the scope of a cosmetic product.

According to the US FDA: A cosmetic is a product (other than soap) applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance.
This is how the FDA defines a cosmetic. There’s a similar definition in the UK & EU – cosmetics can’t affect cell function
According to the US FDA: drug is a substance recognized by an official pharmacopoeia or formulary, or a substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease, or a substance (other than food) intended to affect the structure or any function of the body.
This is the FDA definition of a drug/medicine – they do affect cell function

There are also restrictions over labelling of these serums. Because cosmetic ingredients and concentrations can’t affect or change cell function, it’s misleading (and naughty) to label these growth serums. So, most are more appropriately dubbed lash enhancers instead.

The low cosmetc concentration of prostaglandins in lash serums means they're not nearly as potent or effective as Latisse
Cosmetic lash enhancers can’t grow lashes (but they can enhance & support growth)

But not all lash serums contain prostaglandin analogs. So, next let’s see what other types of ingredients you can choose from.

What ingredients are in eyelash serums?

There’s a cocktail of ingredients found in most serums.

  • A few contain very low amounts of stimulating prostaglandin analogs
  • Most have hair supporting peptides & vitamins
  • And others include hydrating ingredients & conditioning botanical extracts to prevent lash breakage
  • And I’ve also found a few serums with mysterious-sounding biological enzymes😲

Here’s a table comparing the ingredients of the serums and what they claim to do:

Brand Claim How? What? Ingredients
UKLash
Eyelash serum
Longer, fuller & voluminous lashes Fortifies your lash follicles to visibly boost length & improve volume. Peptides, vitamins & extracts

✖ No prostaglandins

View ingredients on incidecoder.com

SILLY GEORGE
Lash Growth serum
Naturally longer, fuller lashes. Activates the hair follicle for rapid growth.
Also toughens the epidermal junction to prevent fall out.
Biological enzyme

✖ No prostaglandins

View ingredients on incidecoder.com

GrandeLASH-MD
Lash Enhancing Serum
Naturally longer, thicker looking lashes Naturally stimulates hair growth, protects, conditions & hydrates. Peptides, vitamins & extracts

✔ Prostaglandin: Cloprostenol isopropylester

View ingredients on incidecoder.com

LASHFOOD
Lash enhancer
Longer, thicker, and stronger lashes Prevents hair loss & triggers regrowth of lashes. Proprietary formulation of herbal extracts called “Phyto-Medic Complex”

✖ No prostaglandins

View ingredients on incidecoder.com

RapidLash
Eyelash enhancing serum
Longer, stronger, fuller, thicker and healthier lashes Conditions, hydrates, fortifies, and nurtures lashes. Proprietary formulation of peptides, vitamins & extracts called “HEXATEIN® 1 COMPLEX”

✔ Prostaglandin: lsopropyl Cloprostenate

View ingredients on incidecoder.com

REVITALASH® Advanced
Eyelash conditioner & serum
Healthier, stronger, improves overall lash appearance. Protects against breakage, conditions, improves health, flexibility & strength, revitalise, add shine, fortify & smooth. Proprietary formulation of peptides, vitamins & extracts called “BioPeptin Complex®”

✖ No prostaglandins

View ingredients on incidecoder.com

neuLASH®
Lash enhancing serum
Stronger, longer-looking lashes. Protects, conditions, enhance, elasticity, shine, strength. Proprietary formulation of peptides, vitamins & extracts called “Active Eyelash Technology®”

✔ Prostaglandin: Isopropyl Cloprostenate

View ingredients on incidecoder.com

Let’s look at them in turn.

What do prostaglandin analogs do?

The synthetic prostaglandin analogs in serums are Choprestenol isopropyl, Isopropyl cloprestonate and Cloprostenol isopropylester. These prostaglandin analogs directly affect how your hair follicle cells function.

Prostaglandin analogs affecting hair growth bind to receptors in your hair follicle primarily the dermal papilla and outer root sheath.
Prostaglandin activates Prostamide Alpha F2 receptors affecting Anagen hair growth

The prostaglandin sinks into your hair follicle and binds with receptors in the hair building areas of your follicles, the dermal papilla and outer root sheath. This causes your hairs to spend longer in the Anagen growing stage and triggers hairs in the Telogen to start the Anagen stage. It all results in longer and fuller lashes.

Diagram showing how prostaglandins affect your hair growth cycle
a: normal hair growth cycle, b: how prostaglandins increase Anagen growth Source

You’ll see prostaglandins very low down the ingredients list. This low concentration in the serums means they take a rather a long time to work on your lashes.

So, you’ll usually find peptides, vitamins and extracts in the ingredients list before Prostaglandin analogs. These other ingredients don’t act directly on the hair follicles to trigger growth as a prostaglandin analog does. But they can fuel hair growth by providing all the goodies your hair needs to grow strong.

More on peptides next…

What are Peptides?

Peptides naturally occur in nearly every tissue and cell in our bodies. We get most of them from the food we eat (broken down into manageable chunks from proteins during digestion), and our cells synthesise other peptides too. Peptides are the little siblings of proteins; much smaller molecules but made of the same building blocks.

Diagrams of the chemical structure of 20 proteinogenic Amino Acids
20 of the 22 protein-forming amino acids (missing L-Selenocysteine & L-Pyrrolysine)

The peptide molecules are short chains of amino acids bound together by ‘peptide’ bonds. They have strings of between 2 to 50 amino acids. Peptides with closer to 50 amino acids are polypeptides. Our cells combine peptides and other amino acids to build complex proteins like collagen, elastin and keratin.

There are 22 protein creating amino acids. Strings of 2 to 50 amino acids linked by peptide bonds are called Peptides. Proteins are larger and more complex molecules made from 50 but typically 500 amino acids.
Amino acids, peptides & proteins

Peptides perform a wide range of essential functions, and we’re still learning more about them. The types of amino acids in the chain, their sequence, and the shape of the peptide determines what it does.

Some peptides act like biological messengers regulating blood glucose, appetite and stimulating tissue growth. So, because these can cause biochemical changes in cells, they are bioactive peptides.  Bioactive peptides are a very interesting science with oodles of potential. Scientists isolate the smallest effective amino acid string and engineer synthetic peptides as new medicines.

According to WebMD there are over 100 peptide drugs available in the U.S., and the list keeps growing. These medicines treat conditions like type 2 diabetes, multiple sclerosis, and high blood pressure.

So, what about peptides in cosmetics and lash serums?

Peptides in cosmetics & lash serums

Cosmetic peptides are not bioactive peptides. They don’t directly affect your cells’ metabolism or function. If they did, they’d be drugs and so regulated by the US Food and Drug Administration (FDA).

cosmetic peptides don’t affect your cells’ metabolism or function
Cosmetic peptides are not bioactive, but they could protect and strengthen the structures of your lashes.

However, they’re small and readily absorbed by the skin. And so, cosmetic brands say they can help protect and strengthen the structures of your lashes to encourage healthy growth. This in turn can give you naturally longer and thicker lashes.

Lash serums with peptides and/or Amino Acids:

UKLash

RapidLash

REVITALASH® Advanced

neuLASH®

GrandeLash-MD

Here are the peptides listed in the ingredients of popular lash serums, and a brief description (if available):

  • Pentapeptide-17 & Myristoyl Pentapeptide-17 : cell communicating ingredients (usually combined) which stimulates your keratin genes for stronger hair
  • Copper Tripeptide-1 : a cell communicating ingredient which stimulates follicular cell proliferation resulting in larger hair follicles, which in turn produce longer and thicker hair
  • Biotinoyl Tripeptide-1 : a cell communicating ingredient claimed to help reduce hair loss and for making the eyelashes appear longer, fuller, and stronger.
  • Polypeptide-23 : not much available on this one, it’s listed as a skin conditioning ingredient
  • Octapeptide-2 : not much available on this one, but manufacturing sources reference it as a ‘hair growth peptide’.

Lash serums also contain a few amino acids too, (GrandeLash-MD is jam-packed with them!), such as:

  • Arginine : one of the primary building blocks of hair keratin and skin collagen
  • L – Proline : an amino acid our bodies can produce that’s also one of the major building blocks of collagen
  • Alanine : a non-essential amino acid that hydrates the skin
  • Aspartic Acid : a non-essential amino acid that hydrates the skin
  • Glycine : a non-essential amino acid that hydrates the skin
  • Histidine : a semi-essential amino acid that hydrates the skin
  • Isoleucine : an essential amino acid and skin identical ingredient that hydrates the skin and protects the skin barrier
  • Phenylalanine : an essential amino acid and skin identical ingredient
  • Serine : a non-essential amino acid that hydrates the skin
  • Threonine : an essential amino acid that hydrates the skin
  • Valine : an essential amino acid that probably hydrates the skin

Vitamins, extracts & moisturisers

Panax Gingseng root, popular in chinese herbal rememdies (and lash growth serums!)
Panax Gingseng root is in UKLash, GrandeLASH-MD, LASHFOOD, & REVITALASH® Advanced lash serums

You’ll also find popular vitamins, botanical extracts and common cosmetic moisturising ingredients thought to encourage or support hair growth, protect and strengthen your hair follicles, and soften and condition your lashes too. But again, they’re all cosmetic ingredients and don’t affect your hair growth directly.

Lash serums with vitamins & botanicals:

UKLash  

GrandeLASH-MD

LASHFOOD 

RapidLash 

REVITALASH® Advanced  

neuLASH®

Here’s a quick overview of these ingredients found in lash serums:

Common vitamins…

  • Biotin or Vitamin H ; when taken as an oral supplement this vitamin can help with stronger nails and hair, but there’s no evidence it works if applied to the skin/hair.
  • Panthenol (Pro-Vitamin B5): Panthenol is moisturising for your skin and might make your hair softer & more elastic.

And a bunch of botanical extracts…

Pumpkin seed is a popular extract in hair growth serums

Hydrating & conditioning lash serums:

UKLash     

GrandeLASH-MD

RapidLash

REVITALASH® Advanced

neuLASH®

And moisturising & protecting ingredients too…

  • Glycerin : a skin identical moisturising ingredient to protect the skin barrier
  • Sodium Hyaluronate or Hyaluronic Acid : a skin identical moisturising and hydrating ingredient
  • Sodium PCA : a skin identical moisturising ingredient to protect the skin barrier
  • Hydrolyzed Glycosaminoglycans : a moisturising and conditioning/softening ingredient
  • Adenosine : a cell communicating, anti-inflammatory ingredient which might be useful for the hair helping with hair thickness and hair growth
  • 2-Hydroxypropanoic Acid : exfoliating and moisturising ingredient
  • Allantoin : skin softening & protecting ingredient
  • Sodium Lactate : a super skin moisturising ingredient

And there’s one final type of ingredient to look at…

Mysterious EPM biological enzyme

What is EPM Biological Enzyme??
EPM Biological Enzyme? Anyone…EPM Biological Enzyme?

SILLY GEORGE says their serum “works by activating the hair follicle to promote rapid growth of eyelashes, making them grow longer, thicker and fuller in as little as 1 week and best results, at around 6 weeks…”

Now, the active lash-growing ingredient in SILLY GEORGE serum is a mysterious substance called “EPM Biological Enzyme”. I say it’s mysterious because it doesn’t exist in an INCI search, or any other type of cosmetic or chemical ingredient search.

What is INCI?
= International Nomenclature of Cosmetic Ingredients
Around 20,000 listings of standardised ingredient names that cosmetics manufacturers must use on the ingredient lists of their products…
An INCI search is an awesome place to start to understand what’s in your cosmetics.

Hmmmm…

Cosmetic manufacturers largely self-regulate in line with country specific legislation. The FDA and EU legislation for cosmetic ingredients labelling ensures we have enough information to compare products, check for ingredients we’re sensitive to, and make informed choices. INCI ingredients are the standard format, and a listing and description gives us some reassuring visibility about an ingredient.

incidecoder page showing EPMbiological enzyme is not an INCI standard name
EPMBiological enzyme is not a recognized INCI name – what on earth is it?

So, because theirs isn’t publicly available, I contacted SILLY GEORGE for more info.

But after several polite reminders, I’ve had nadda in return.

Now, all the other lash serums clearly list their ingredients in the INCI standard (even those with proprietary formulations). And that’s good because I want to know what is in it, I want to know what it does and I want to know it is SAFE.

So, I’m frustrated, and an extra curious bunny with many questions whirling around my now suspicious brain 🐰🔍🕵️‍♀️…

What-the-follicle is EPM biological enzyme?

After more coffee-fuelled, tenacious interwebs research, here’s what we do know…

#1 It’s made of 10 Amino acids.

SILLY GEORGE share this. And we know Amino Acids are the building blocks of peptides and proteins, remember? So, this also matches up with its enzyme status. Enzymes are biological catalysts and almost always a protein. They speed up how fast specific chemical reactions take place in cells. But the enzyme doesn’t change during the reaction. It stays the same and continues enzyming, repeatedly.

But what we don’t know is which Amino Acids, or which protein is it derived from? How big is it, perhaps it’s really a peptide? How is it made? Also, we don’t know what hair follicle cells it works on or how it works its magic 🤔.

#2 They call it a growth serum

Earlier in this article I explained the difference between cosmetics and drugs, and lash enhancers and lash growth serums. A growth serum implies it affects your cells’ function directly and causes growth. This would make it a drug/medication, just like Latisse, requiring through tests and approval. So, brands call their cosmetic serums lash enhancers instead.

Silly George call their product a lash GROWTH serum, but this extends beyond the scope of a cosmetic product. So, does it actually grow lashes?
The ‘growth’ claim extends beyond the scope of a cosmetic product

But not SILLY GEORGE.

They call theirs a lash growth serum, but it’s still sold as a cosmetic.

So, this could simply be an exaggerated and somewhat misleading claim designed to standout versus other lash serums. I’m not sure because there’s no independent information available on EPM Biological Enzyme. But something isn’t quite right here.

#3 EPM Biological Enzyme is not unique to SILLY GEORGE.

A quick Google search of the SILLY GEORGE ingredients list led me to bulk-buy, white-label lash serum products made in China, listed on sites like alibaba.com. A few serums contain Biological Enzyme “EPM” made of 10 Amino Acids.

#4 EPM peptide?

Whilst trying to find anything about EPM, I discovered a few research studies from 2003 and 2005 about a peptide derived from Epimorphin. Epimorphin controls development in various organs, and plays an important role in hair growth.

Here’s how…

Stem cells in our hair follicles create Epimorphin, which then binds to other hair follicle cells and triggers the active, Anagen hair growth. The team behind the studies extracted a smaller peptide from Epimorphin, made of 👉10 Amino Acids. They tested it in a lab culture and on mice and, just like Epimorphin, it induces Anagen growth in hair follicles. They call the peptide EPM.

The company behind the studies patented the peptide, but since this early excitement about its hair growing potential, I found nothing more on EPM peptide. Therefore, it’s not clear to me if it’s the same active ingredient in SILLY GEORGE serum, or just a similarly named drug 🤷‍♀️.

So, there are many questions still unanswered. I’ve requested assistance from various contacts and will update this article should I get more concrete information.

Do lash serums work?

Let’s look at the objective evidence first.

Although almost all these brands claim their formulations are clinically proven, none share corresponding details of any robust trial design resembling typical strict clinical standards. So, I’m sceptical such testing exists.

Users share subjective satisfaction scores in consumer studies

Blurred in with the “clinically proven” statement, they also share the positive results from their consumer studies. The studies range in number of particpants, the largest are from RapidLash and neuLash.

But don’t mistake these as the afore mentioned clinical results. Consumer studies are at-home tests by participants following the treatment regime, and then completing a satisfaction survey. The results are subjective feedback scores (not objective measurements). These consumer studies sound positive, but they are not as reassuring as published clinical studies which have a strict design, control group and measurement method.

Pssst: GrandeLash-MD are the only brand to openly share they have no clinical test data. The other brands all refer instead to their consumer study data when asked about any clinical data.

So, what about lash-growing proof for the ingredients?

Well, manufacturers claim their peptides and Amino Acids support hair growth. And yes, the conditioning and hydrating ingredients can help the appearance of your lashes too. But there’s little human testing supporting their efficacy, even for the most popular peptide ingredients. There’s also little testing supporting the synthetic prostaglandin analogs in these lash serums. So, they may or may not work for you as promised.

Of course, you could rely on the many 5-star reviews on the lash serum brand websites. But remember, they control the reviews that show up so you may not get a fair representation of all experiences.

And finally, don’t let the marketing hype blind you. These are cosmetic formulations and not medicines. Whilst many people do see healthy, longer or improved lashes, others don’t see much change at all. It’s important to have realistic expectations about what these serums can do for you.

Here’s a comparison table of treatment schedules, guarantees and study data of the serums.

Brand Money back guarantee? Schedule Clinical study? Consumer study Consumer study results
UKLash
Eyelash serum
✔ 12-week limited guarantee (based on before/after photos) Once a day for 8-12 weeks

Then, 3-4 times per week maintenance
✖ No study available

Claim: up to 55% longer and 75% more voluminous looking lashes
Unknown number of subjects over 12 weeks. 9 out 10 saw improved lashes
SILLY GEORGE
Lash Growth serum
✔ 60-day money back guarantee 1-2 times per day, best results around 6 weeks

Then, 1-2 times per week maintenance
✖ No study available

Claim: 99% success rate, with the average growth of the eyelashes being 56% in 6 weeks
30 subjects over 28 days 93% satisfied with length & volume

83% saw thicker lashes

93% saw healthier lashes
GrandeLASH-MD
Lash Enhancing Serum
Once daily for 3 months. See results at 4-6 weeks, with full improvement in 3 months.

Then, every other day for maintenance
✖ Not tested 30 subjects over 12 weeks 94% saw healthier looking lashes

91% saw longer looking lashes

97% saw more visible lashes
LASHFOOD
Lash enhancer
Apply nightly. See results in 4 weeks with best results at 3 months. Use consistently for best results. ✖ No study data 16 participants over 16 weeks ✔ With photos

85% saw improved fullness & texture

100% saw an increase in length

100% saw increased thickness & density
RapidLash
Eyelash enhancing serum
Apply nightly before bed. See results after 4 weeks, with best results after 8 weeks ✖ No study data 102 subjects over 56 days 86% saw longer-looking & fuller-looking lashes in 8 weeks
REVITALASH® Advanced
Eyelash conditioner & serum
Apply daily, morning or night
✖ No study data 63 subjects over 6 weeks 98% saw improved lash appearance

98% saw healthier-looking lashes

98% saw stronger lashes
neuLASH®
Lash enhancing serum
✔180-day money back guarantee Apply once every evening.

Then, every other day to maintain
✖ No study data 102 subjects over 56 days 88% saw stronger lashes

86% saw improved overall appearance of lashes

86% saw fuller lashes

86% saw thicker, longer, & stronger lashes

Are lash serums safe?

Are lash serums safe?
You may be allergic to some cosmetic ingredients in lash serums.
Prostaglandin analogs can cause side effects.
EPM Biological Enzyme - there's just not any info to say either way...

All the serums (apart from SILY GEORGE) list known and safe INCI ingredients. So, yes, they’re safe. However, you could still have allergic or sensitive reactions to a specific ingredient.

And it’s worth highlighting prostaglandin analogs can cause side effects. We know this because of the thorough clinical tests and trials for the eye medications containing prostaglandin analogs.

The possible side effects of prostaglandin analogs are:

‼ Itchy, red eyes
‼ Darkening of the eyelids
‼ Reduced eye pressure, which could mask glaucoma
‼ Unwanted hair growth in areas the product repeatedly touches
‼ Darkening of your eye colour, especially if your irises are hazel or green. Here’s a good article that explains the eye darkening side effect

However, bear in mind these side effects come from prostaglandin drops placed directly into the eye. With lash serums you apply a much smaller amount along your lash line (not in your eye). And these serums have a significantly lower concentration prostaglandin. So together, this means the prostaglandin dose is much less likely to get into your eye and cause side effects.

However, the synthetic analogs in lash serums are largely untested (especially compared to Latisse and Lumigan). So, it’s still a risk worth considering.

And finally, because of lack of information and radio silence from SILLY GEORGE, it’s not possible to comment either way on the safety of EPM Biological Enzyme ingredient in their serum. Although SILLY GEORGE say it is safe, it lacks the reassuring clarity of a recognized INCI standard name and categorization.

So, which lash Serum do you fancy? Please check deals below and shop via my links. I may earn a small commission from some (but your price stays the same). I really appreciate your support 🙏!

UKLash SILLY GEORGE RapidLash GrandeLASH-MD LASHFOOD REVITALASH® Advanced neuLASH®
What is it?
Eyelash serum

Lash Growth serum

Eyelash enhancing serum

Lash Enhancing Serum

Lash enhancer

Eyelash conditioner & serum

Lash enhancing serum
Price
Amount
Lasts
£37.99
3 ml
3 months
£44.99
3ml
2-3 months
$49.95/ £39.99
3 ml
2 months
$65/£55
2ml
3 months
$78
3 ml
3 months
$98 / £125
2ml
3 months
$150
6ml
6months
What it does Fortifies your lash follicles to visibly boost length & improve volume. Activates the hair follicle for rapid growth.
Also toughens the epidermal junction to prevent fall out.
Conditions, hydrates, fortifies, and nurtures lashes. Naturally stimulates hair growth, protects, conditions & hydrates. Prevents hair loss & triggers regrowth of lashes. Protects against breakage, conditions, improves health, flexibility & strength, revitalise, add shine, fortify & smooth. Protects, conditions, enhance, elasticity, shine, strength.
Good to know ✔Cruelty free
✔Vegan friendly
✔Cruelty free
✔Vegan friendly
✔Cruelty free
✔Cruelty free
🐇PETA certified
✔Ecocert certified
✔Cruelty free
🐇PETA certified
✔Vegan friendly
✔Cruelty free
🐇PETA certified
✔Vegan friendly
✔Cruelty free
Guarantee? ✔ 12-week limited guarantee (based on before/after photos) ✔ 60-day money back guarantee ✔180-day money back guarantee
Deals 🌍 🇬🇧 🇦🇺 🇺🇸 UKLash.com 🌍 🇬🇧 🇦🇺 🇺🇸 sillygeorge.com 🇬🇧 allbeauty.com
🇺🇸 LookFantastic US
🇬🇧 allbeauty.com
🇺🇸 Skinstore US
🇺🇸 LASHFOOD.com 🇬🇧 Amazon UK
🇺🇸 Amazon.com
🇺🇸 skinresearchlabs.com
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Home Laser & IPL reviews

Philips Lumea Prestige review – my overall favourite
4.9

Philips Lumea Prestige review – my overall favourite

Smoothskin Pure review; fastest, easiest, best value premium IPL
4.8

Smoothskin Pure review; fastest, easiest, best value premium IPL

Braun Silk Expert Pro 5 IPL review – Fast & no-faff
4.7

Braun Silk Expert Pro 5 IPL review – Fast & no-faff

Venus Silk expert/ Braun Silk expert 5 IPL review (5001, 5009, 5008); fast, safe & simple
4.5

Venus Silk expert/ Braun Silk expert 5 IPL review (5001, 5009, 5008); fast, safe & simple

Tria 4X laser hair removal review – most powerful
4.5

Tria 4X laser hair removal review – most powerful

Braun Silk Expert Pro 3 IPL review; fast & perfect for mid to dark skin
4.5

Braun Silk Expert Pro 3 IPL review; fast & perfect for mid to dark skin

Silk’n Infinity review: safe for dark & black skin
4.4

Silk’n Infinity review: safe for dark & black skin

Smoothskin Bare+ home IPL review; fast & affordable
4.4

Smoothskin Bare+ home IPL review; fast & affordable

Smoothskin Bare IPL review; Ultra-fast & superb for dark skin
4.3

Smoothskin Bare IPL review; Ultra-fast & superb for dark skin

Panasonic ES-WH90 IPL review – ideal for facial use
4.3

Panasonic ES-WH90 IPL review – ideal for facial use

Iluminage Precise Touch review; for ALL skin tones, & fair hair
4.3

Iluminage Precise Touch review; for ALL skin tones, & fair hair

Philips Lumea Advanced review – suits face, bikini & underarms
4.2

Philips Lumea Advanced review – suits face, bikini & underarms

Iluminage Touch review;  for dark & black skin, & fair hair too
4.1

Iluminage Touch review; for dark & black skin, & fair hair too

Gillette Venus Braun Silk Expert 3 IPL review (BD3001, BD3005)
4.1

Gillette Venus Braun Silk Expert 3 IPL review (BD3001, BD3005)

Silk’n Flash & Go Express review / Glide Xpress review (300,000 flashes)
4.0

Silk’n Flash & Go Express review / Glide Xpress review (300,000 flashes)

Philips Lumea Essential BRI861 review
4.0

Philips Lumea Essential BRI861 review

Remington iLight review: Ultra, IPL6500, IPL6780, IPL6750, IPL6250
3.7

Remington iLight review: Ultra, IPL6500, IPL6780, IPL6750, IPL6250

Philips Lumea Comfort review SC1981 and SC1983
3.6

Philips Lumea Comfort review SC1981 and SC1983

Silk’n Glide 150,000 review / Silk’n Flash&Go Compact review
3.5

Silk’n Glide 150,000 review / Silk’n Flash&Go Compact review

Veet Infini’Silk review 50,000 pulses
2.9

Veet Infini’Silk review 50,000 pulses